Future Inventions & Biotechnology Innovation
Genuine inventions, documented patent filings, and future research concepts from Alkhaleeli BioAI LLC — clearly distinguishing granted patents, provisional applications, and unfiled concepts.
Development stages are labeled explicitly: Granted Patent (issued U.S. patent), Provisional Filing (early-stage USPTO application — not an issued patent), In Development (internal documented program), and Concept — Unfiled(unfiled research concept). No concept is claimed as patented, tested, or commercially launched without documentation.
Biotechnology Inventions
AI-Guided mRNA Research Systems
A research-only AI-guided workflow for identifying cancer-associated targets, prioritizing possible mRNA vaccine candidates, and using CRISPR-based concepts for antigen-validation research.
Research objective: Enable systematic, reproducible, AI-assisted design of personalized mRNA vaccine research candidates.
Potential application: Personalized oncology research programs and mRNA vaccine R&D pipelines.
USPTO Provisional Application 63/936,055
AI-Designed Synthetic Binding Protein Biosensor Platform
An AI-designed colorimetric biosensor platform using synthetic binding proteins for rapid detection and classification of Gram-negative bacteria, Gram-positive bacteria, and fungal pathogens.
Research objective: Provide fast, portable molecular detection and classification of microbial pathogens.
Potential application: Rapid diagnostic research and prototype development (not clinical diagnostic use unless validated and cleared).
USPTO Provisional Application 64/004,904
Lateral Flow IgE Immunoassay Apparatus
A rapid lateral-flow immunoassay concept for detecting and estimating allergen-specific IgE antibodies in a portable test format.
Research objective: Support fast, accessible allergy-related screening research.
Potential application: Point-of-need allergy screening research formats.
USPTO Provisional Application 63/931,575
Computational Drug-Development Platforms
AI frameworks for computational therapeutic design, drug-target evaluation, candidate prioritization, and biomedical decision-support systems.
Research objective: Accelerate early-stage drug discovery investigation with reproducible computational workflows.
Potential application: Pharmaceutical and biotech R&D teams evaluating therapeutic concepts.
Internal research program
RNA Therapeutic & Protein-Engineering Concepts
Concepts spanning mRNA construct assessment, sequence-optimization logic (including the Rami Five-Checkpoint Framework, R5CF), and engineered protein research designs.
Research objective: Systematize the design and evaluation of RNA-based therapeutic research concepts.
Potential application: mRNA vaccine and RNA therapeutic research blueprints.
Internal research program
Integrated Biomedical Engineering Systems
Integrated biomedical engineering concepts combining AI, computational modeling, and diagnostic platform design.
Research objective: Unify AI modeling and diagnostic platform engineering into coherent research systems.
Potential application: Future diagnostic and biomedical research platform development.
Internal research concept
Future Technology
Implant-Support & Osseointegration Technology
A granted U.S. patent, "Method and Apparatus for Improving Osseointegration, Functional Load, and Overall Strength of Intraosseous Implants," covering implant-surface technology designed to improve osseointegration and biological integration. Rami M. Alkhaleeli, Founder and CEO of Alkhaleeli BioAI LLC, is a named co-inventor (with Vagan Tapaltsyan, Morshed Khandaker, Shahram Riahinezhad, and Niyaf Nidhal Kadhem Alkadhem). The patent is presented as part of the founder's professional innovation background and is not intellectual property owned or licensed by Alkhaleeli BioAI LLC; no institutional endorsement or commercial partnership with UCO is implied.
Research objective: Improve long-term implant stability and functional load distribution.
Potential application: Biomedical device design and functional support engineering.
US Patent No. 11,058,521 (granted July 13, 2021) — assigned to the University of Central Oklahoma
View public patent recordMagneto-Mechanical RF Energy Harvester
A five-stage energy-harvesting concept combining magneto-mechanical motion and RF energy capture for battery-free or emergency power applications.
Research objective: Enable micro-power generation without batteries for portable devices.
Potential application: Battery-free phone concepts and emergency power research.
USPTO Provisional Application 64/017,342
AI Computing Cooling Innovations
Early conceptual work on cooling approaches for high-density AI computing hardware.
Research objective: Explore thermal-management concepts for computational research infrastructure.
Potential application: Future AI computing platform research.
Internal research concept
Scientific Automation & Research Platforms
Software platforms for bioinformatics analysis, automated scientific report generation, sequence scoring, and research workflow automation.
Research objective: Automate and standardize computational research pipelines.
Potential application: Internal research tooling and client research workflows.
Internal research program
Biomedical Engineering Concepts
Future biomedical engineering concepts under early exploration, including novel device and diagnostic formats.
Research objective: Identify next-generation biomedical device and diagnostic research directions.
Potential application: Long-range biomedical R&D planning.
Internal research concept
Collaborate on Our Innovation Portfolio
Biotechnology companies, research organizations and investors interested in licensing, joint research, or co-development of these invention concepts are invited to get in touch.
Discuss R&D CollaborationUSPTO Patent Portfolio & Innovation Filings
Biotechnology • AI Diagnostics • mRNA Research • Biosensors • Energy Innovation
Rami M. Alkhaleeli's innovation portfolio includes one granted U.S. patent and multiple USPTO provisional patent applications across biomedical device design, AI-guided mRNA research, rapid immunoassay concepts, AI-designed biosensor platforms, and magneto-mechanical energy-harvesting technology.
Method and Apparatus for Improving Osseointegration, Functional Load, and Overall Strength of Intraosseous Implants
Rami M. Alkhaleeli, Founder and CEO of Alkhaleeli BioAI LLC, is a named co-inventor of U.S. Patent No. 11,058,521, assigned to the University of Central Oklahoma. This patent relates to implant-surface technologies designed to improve osseointegration and biological integration. This patent is presented as part of the founder's professional innovation background. It is not represented as intellectual property owned or licensed by Alkhaleeli BioAI LLC. No institutional endorsement or commercial partnership with UCO is implied.
View public patent recordAI-guided personalized mRNA cancer vaccines with CRISPR-based antigen validation
This provisional filing describes a research-only AI-guided workflow for identifying cancer-associated targets, prioritizing possible mRNA vaccine candidates, and using CRISPR-based concepts for antigen-validation research. This is an early-stage computational and experimental concept, not a clinical treatment or approved vaccine.
Lateral Flow Immunoassay Apparatus for Rapid Detection and Quantification of Allergen-Specific IgE Antibodies
This provisional filing focuses on a rapid lateral-flow immunoassay concept for detecting and estimating allergen-specific IgE antibodies. The goal is to support fast, accessible allergy-related screening research using a portable test-format concept.
Artificial Intelligence Designed Synthetic Binding Protein Colorimetric Biosensor Platform for Rapid Diagnostic Detection and Classification of Gram Negative Bacteria, Gram Positive Bacteria, and Fungal Pathogens
This provisional filing describes an AI-designed biosensor platform using synthetic binding proteins and colorimetric detection concepts to identify and classify bacterial and fungal pathogens. The concept is intended for research and prototype development, not clinical diagnostic use unless validated and cleared by regulators.
The Five-Stage Magneto-Mechanical RF Harvester for Battery-Free Phones
This provisional filing presents an energy-harvesting concept combining magneto-mechanical motion and RF-related energy-capture ideas for battery-free or emergency power applications. It represents early-stage engineering research into alternative micro-power generation.
USPTO Receipts & Patent Records
Important Disclaimer: Some records shown are provisional patent applications and are not issued patents. Provisional applications are early-stage USPTO filings and do not by themselves represent granted patent rights. Medical, scientific, diagnostic, and therapeutic concepts shown here are research-only and are not FDA-cleared, clinically validated, or intended for diagnosis, treatment, cure, or clinical decision-making unless specifically approved through the appropriate regulatory process.
Alkhaleeli BioAI LLC presents this portfolio for informational, educational, and research-innovation purposes. All medical and biotechnology concepts require laboratory validation, safety testing, regulatory review, and appropriate approvals before any clinical or commercial use.